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. 2024 Nov 12;16(11):e73562. doi: 10.7759/cureus.73562

Table 3. Medications used in patients with cystic fibrosis.

Data are presented as numbers (%).

aFisher’s exact test

P-value < 0.05 is considered statistically significant.

Bold values indicate statistical significance.

*These vitamins were stopped at least three days before enrollment in the study.

ADEK: fat-soluble vitamins A, D, E, and K

Medication used Vitamin E Level P-valuea Total, n = 35 (100)
Low, n = 9 (25.7) Normal, n = 26 (74.3)
Pancreatic enzyme replacement therapy 8 (88.9) 24 (92.3) 1.000 32 (91.4)
Previous ADEK supplementation* 6 (66.7) 24 (92.3) 0.095 30 (85.7)
Bronchodilator (salbutamol) 1 (11.1) 15 (57.7) 0.022 16 (45.7)
Dornase alfa 4 (44.4) 10 (38.5) 1.000 14 (40.0)
Oral antibiotic (azithromycin) 4 (44.4) 8 (30.8) 0.685 12 (34.3)
Multivitamins 2 (22.2) 8 (30.8) 1.000 10 (28.6)
Inhaled antibiotic (tobramycin) 2 (22.2) 8 (30.8) 1.000 10 (28.6)
Proton pump inhibitor 2 (22.2) 3 (11.5) 0.586 5 (14.3)
Inhaled steroid 0 (0.0) 5 (19.2) 0.297 5 (14.3)
Ursodeoxycholic acid 2 (22.2) 2 (7.7) 0.268 4 (11.4)
Vitamin D supplementation 2 (22.2) 2 (7.7) 0.268 4 (11.4)
Iron supplementation 0 (0.0) 1 (3.8) 1.000 1 (2.9)