Figure 5.

Association between Bcl‐2 protein expression analyzed at diagnosis and the response at three different time points in the treatment scheme (GEM2012 protocol). The response to treatment was assessed by IMWG response criteria (A) and minimal residual disease (MRD) by flow cytometry (B), at three points: after induction (in red), after autologous stem cell transplantation (ASCT) (in blue), and after consolidation (in green). The statistically significant differences between groups were determined by the Mann–Whitney U test. *p < 0.05, **p < 0.01, ***p < 0.001.