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Schematic representation of the experimental protocol. Abbreviations: pressure-controlled volume-guaranteed ventilation (PCV-VG); flow-controlled ventilation with positive end-expiratory pressures (FCV +); flow-controlled ventilation with negative end-expiratory pressures (FCV−); intracranial hypertension (ICH); end-expiratory pressure (EEP, which positive in case of PCV-VG and FCV+ ; and negative in case of FCV−). The arrows indicate measurement points
