Table 1.
The median inhibitory concentration (IC50, μM) and selectivity index (SI) (mean ± SD) values of cancer cell lines including breast cancer (MCF-7), non-small cell lung cancer (A549) and glioblastoma (U-87 MG) as well as normal cells; human dermal fibroblast (HDF) for HPCR and Cisplatin upon 96 h treatment period.
| IC50 (μM) | SI | ||||||
|---|---|---|---|---|---|---|---|
| Drug/cell line | HDF | U-87 | A549 | MCF-7 | U-87 | A549 | MCF-7 |
| HPCR | 146.7 ± 12 | 71 ± 10 | 92.3 ± 7.3 | 112.3 ± 5.4 | 2.07 | 1.58 | 1.31 |
| Cisplatin | 40.9 ± 5.4 | 28.3 ± 5.3 | 30.4 ± 5.2 | 26.9 ± 4.7 | 1.44 | 1.34 | 1.5 |