Table 1.
Clinical data and serologic indices of the two groups
| Parameters | Effective group (n=34) | Ineffective group (n=56) | t/χ2 | P |
|---|---|---|---|---|
| Gender (Male/Female) | 19/15 | 34/22 | 0.204 | 0.651 |
| Age (years) | 58.31±9.12 | 58.34±9.34 | 0.015 | 0.988 |
| Body mass index (kg/m2) | 22.25±2.33 | 22.26±2.29 | 0.020 | 0.984 |
| Smoking history | 17 (50.00) | 25 (44.64) | 0.244 | 0.621 |
| Drinking history | 20 (58.82) | 38 (67.86) | 0.753 | 0.385 |
| KPS scores (<70/≥70) | 15/19 | 32/24 | 1.439 | 0.230 |
| Tumor site (Gastric/Gastroesophageal junction) | 26/8 | 45/11 | 0.192 | 0.661 |
| Presence of ascites | 23 | 41 | 0.319 | 0.572 |
| Number of immunotherapy lines (<2/≥2) | 20/14 | 16/40 | 8.067 | 0.005 |
| Use of other therapies | 26 | 47 | 0.768 | 0.381 |
| sTim-3 (mg/L) | 1.98±0.32 | 2.28±0.39 | 3.777 | <0.001 |
| PG I (ng/mL) | 43.77±8.43 | 37.58±7.97 | 3.495 | 0.001 |
| PG II (ng/mL) | 12.17±2.52 | 14.80±3.32 | 3.973 | <0.001 |
| PD-L1 (pg/mL) | 195.44±32.86 | 231.48±44.57 | 4.085 | <0.001 |
Note: KPS: Quality of Life Karnofsky Score; STim-3: immunoglobulin mucin molecule 3; PG: pepsinogen; PD-L1: programmed death ligand-1.