Table 6.
Predictive value of serum sTim-3, PG I, and PD-L1 alone or in combination for patient prognosis
| Parameters | AUC | Standard error | 95% CI | P | Cut-off | Youden index | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|---|---|---|---|
| sTim-3 | 0.776* | 0.050 | 0.676-0.857 | <0.001 | >2.889 mg/L | 0.445 | 58.06 | 86.44 |
| PG I | 0.683* | 0.683 | 0.576-0.777 | 0.001 | ≤46. 853 ng/mL | 0.325 | 61.29 | 71.19 |
| PD-L1 | 0.753* | 0.052 | 0.651-0.838 | <0.001 | >243.425 pg/mL | 0.381 | 83.87 | 54.24 |
| Combine | 0.878 | 0.036 | 0.792-0.937 | <0.001 | - | 0.622 | 77.42 | 84.75 |
Note: STim-3: immunoglobulin mucin molecule 3; PG: pepsinogen; PD-L1: programmed death ligand-1.
*
P<0.05, compare with combined testing.