Table 5.
Univariate and multivariate Cox regression analysis of prognostic factors in PC patients
| Variable | Single factor analysis | Multiple-factor analysis | ||
|---|---|---|---|---|
|
|
|
|||
| HR (95% CI) | P | HR (95% CI) | P | |
| Gender | 0.890 (0.549-1.444) | 0.637 | - | - |
| Age | 1.226 (0.742-2.025) | 0.426 | - | - |
| Differentiation extent | 1.529 (0.847-2.760) | 0.158 | - | - |
| Tumor location | 1.444 (0.889-2.345) | 0.138 | - | - |
| Tumor invasion of large blood vessels | 1.375 (0.847-2.235) | 0.198 | - | - |
| Distant metastasis | 1.993 (1.227-3.238) | 0.005 | 0.665 (0.372-1.189) | 0.169 |
| Chemotherapy regimen | 0.970 (0.766-1.228) | 0.798 | - | - |
| Pre-treatment FAR | 6.062 (3.548-10.357) | < 0.001 | 4.972 (2.670-9.261) | < 0.001 |
| Pre-treatment NLR | 4.757 (2.836-7981) | < 0.001 | 3.308 (1.876-5.835) | < 0.001 |
| Pre-treatment PLR | 1.510 (0.909-2.507) | 0.111 | - | - |
Note: AG, gemcitabine + albumin-bound paclitaxel; GS, gemcitabine + Teggio; AS, albumin-bound + Teggio; PC, pancreatic cancer; FAR, fibrinogen/albumin ratio; NLR, neutrophil/lymphocyte ratio; PLR, platelet/lymphocyte ratio.