Table 3.
Partial candidate target genes potentially regulated by CREB3L4 identified through the joint analysis of chromatin immunoprecipitation assay sequencing (CHIP-seq) and mRNA sequencing (mRNA-seq)
| GeneSymbol | Regulation: shCREB3L4_vs_shNC | CHIP-seq results | mRNA-seq results | ||||
|---|---|---|---|---|---|---|---|
|
|
|
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| Peak_classification | Fold change | P-value | FDR | P-value | FDR | ||
| RASEF | Down | Promoter | -164.3 | 0.0000 | 0.0055 | 0.0572 | 0.9996 |
| ACTG2 | Down | Promoter | -164.3 | 0.0000 | 0.0055 | 0.0015 | 0.228 |
| HIST1H2AB | Down | Promoter | -164.3 | 0.0000 | 0.0055 | 1 | 1 |
| CACNG7 | Down | Promoter | -164.3 | 0.0000 | 0.0055 | 0.0081 | 0.5828 |
| DPEP1 | Down | Promoter | -156.1 | 0.0000 | 0.0071 | 0.2513 | 0.9996 |
| ITPR2 | Down | Promoter | -156.1 | 0.0000 | 0.0071 | 0.0125 | 0.8371 |
| PCDHA1 | Down | Promoter | -148 | 0.0000 | 0.0086 | 1 | 1 |
| GPCPD1 | Down | Promoter | -22.34 | 0.0000 | 0.0002 | 0.0219 | 0.8883 |