Figure 1.

Expression and diagnostic performance of pituitary tumor-transforming gene (PTTG) genes in lung adenocarcinoma (LUAD) and control cell lines. A. RT-qPCR analysis of PTTG1, PTTG2, and PTTG3P gene expression levels in LUAD (orange) and control (green) cell lines. B. Receiver operating characteristic (ROC) curves assessing the diagnostic accuracy of PTTG1, PTTG2, and PTTG3P expression levels. The area under the curve (AUC) values are 0.88 for PTTG1, 0.77 for PTTG2, and 0.98 for PTTG3P, demonstrating that PTTG3P has the highest diagnostic potential for distinguishing LUAD from control samples, followed by PTTG1 and PTTG2. *P-value < 0.05.