Table 1.
Characteristics of data used in the Mendelian randomization study
| Exposure/Outcome | Participants | Resource |
|---|---|---|
| Cholecystectomy | 18,319 cases and 444,614 non-cases of European ancestry | UK Biobank |
| Cholecystectomy | 29,157 cases and 383,024 non-cases of European ancestry | FinnGen R10 |
| TC | 1.32 million individuals of European ancestry | GLGC |
| LDL-C | 1.32 million individuals of European ancestry | GLGC |
| HDL-C | 1.32 million individuals of European ancestry | GLGC |
| TG | 1.32 million individuals of European ancestry | GLGC |
| Fasting Glucose | 58,074 individuals of European ancestry | MAGIC |
| Fasting Insulin | 51,750 individuals of European ancestry | MAGIC |
| HbA1c | 46,368 individuals of European ancestry | MAGIC |
Abbreviations: TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TG, triglyceride; HbA1c, hemoglobin A1c; GLGC, Global Lipids Genetics Consortium; MAGIC, Meta-Analyses of Glucose and Insulin-related traits Consortium.