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Effect of reducing eIF3a expression on cellular response to hydroxyurea and nocodazole. Stable H1299 clones transfected with vector (HVec) or antisense eIF3a (HAS4 and HAS5) [9] were treated with various concentrations of hydroxyurea (HU) or nocodazole (Noco) for 48 h. Cells were then collected for analysis of cell cycle distribution.
