Figure 4.
Breakdown of model QALYs for UKPDS-OM2 by event: quality-adjusted life-years (QALYs) lost through the baseline disutility associated with diabetes, QALYs lost through the disutilities attached to each event, and years of life lost through mortality before year 7.
The impact of each individual event includes only the disutilities directly applied to that event: it excludes any mortality from fatal events of that type (which are counted in the years of life lost) and the impact of one event on the risk of another event. For example, the impact of stroke captures only the quality-of-life reduction from nonfatal stroke (0.165): the QALYs lost from fatal stroke and the QALYs lost from stroke survivors having higher mortality are counted in years of life lost, while the QALYs lost from MI and amputation (which occur at a higher rate following a stroke 4 ) are counted under MI and amputation. IHD, ischemic heart disease; MI, myocardial infarction; QALYs, quality-adjusted life-years; SA, sensitivity analysis; UKPDS-OM2, United Kingdom Prospective Diabetes Study Outcomes Model version 2.