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. 2024 Dec 15;14(4):e70026. doi: 10.1002/pul2.70026

Table 2.

Hemodynamic data before and after SGLT2 inhibitor treatment.

Before administering SGLT2 inhibitor After administering SGLT2 inhibitor p‐value
Number 10 10
Echocardiography
LVEF (%) 68.9 ± 3.2 69.0 ± 5.4 0.864
LVDd (mm) 44.1 ± 4.1 45.7 ± 3.8 0.163
LA (mm) 34.3 ± 7.4 37.6 ± 7.5 0.228
E/e’ 8.3 ± 2.9 10.5 ± 3.5 0.246
RVFAC (mm) 39.4 ± 2.7 38.4 ± 6.8 0.479
TAPSE 22.2 ± 3.1 21.2 ± 4.6 0.089
TRPG (mmHg) 36.9 ± 14.8 37.5 ± 13.4 0.132
MRI
LVEDVi 70.1 ± 15.3 75.7 ± 20.4 0.121
LVESVi 29.5 ± 7.5 31.0 ± 7.5 0.348
LV: GLS −13.8 ± 2.0 −17.3 ± 2.0 0.003
LV: GRS 25.1 ± 2.6 29.3 ± 6.3 0.070
LV: GCS −18.8 ± 2.0 −20.3 ± 3.1 0.095
RVEDVi 79.0 ± 16.9 80.9 ± 24.6 0.634
RVESVi 36.4 ± 16.1 36.7 ± 12.4 0.893
RV: GLS −13.8 ± 2.1 −15.2 ± 3.3 0.284
Peak LA strain −14.1 ± 2.9 −17.3 ± 5.0 0.297
Peak RA strain −15.8 ± 5.6 −14.2 ± 5.4 0.105

Note: Paired t‐test were used for changes in parameters of echocardiography and MRI before and after treatment with SGLT2 inhibitor.

Abbreviations: GCS, global circumferential strain; GLS, global longitudinal strain; GRS, global radial strain; LA, left atrium; LA, left atrial; LV, left ventricular; LVEF, left ventricular ejection fraction; LVDd, left ventricular diameter at end‐diastole; LVEDVi, left ventricular end‐diastolic volume index; LVESi, left ventricular end‐systolic volume index; RA, right atrial; RVFAC, right ventricular fractional area change; TAPSE, tricuspid annular plane systolic excursion; TRPG, tricuspid regurgitation peak gradient.