Table 2.
Before administering SGLT2 inhibitor | After administering SGLT2 inhibitor | p‐value | |
---|---|---|---|
Number | 10 | 10 | |
Echocardiography | |||
LVEF (%) | 68.9 ± 3.2 | 69.0 ± 5.4 | 0.864 |
LVDd (mm) | 44.1 ± 4.1 | 45.7 ± 3.8 | 0.163 |
LA (mm) | 34.3 ± 7.4 | 37.6 ± 7.5 | 0.228 |
E/e’ | 8.3 ± 2.9 | 10.5 ± 3.5 | 0.246 |
RVFAC (mm) | 39.4 ± 2.7 | 38.4 ± 6.8 | 0.479 |
TAPSE | 22.2 ± 3.1 | 21.2 ± 4.6 | 0.089 |
TRPG (mmHg) | 36.9 ± 14.8 | 37.5 ± 13.4 | 0.132 |
MRI | |||
LVEDVi | 70.1 ± 15.3 | 75.7 ± 20.4 | 0.121 |
LVESVi | 29.5 ± 7.5 | 31.0 ± 7.5 | 0.348 |
LV: GLS | −13.8 ± 2.0 | −17.3 ± 2.0 | 0.003 |
LV: GRS | 25.1 ± 2.6 | 29.3 ± 6.3 | 0.070 |
LV: GCS | −18.8 ± 2.0 | −20.3 ± 3.1 | 0.095 |
RVEDVi | 79.0 ± 16.9 | 80.9 ± 24.6 | 0.634 |
RVESVi | 36.4 ± 16.1 | 36.7 ± 12.4 | 0.893 |
RV: GLS | −13.8 ± 2.1 | −15.2 ± 3.3 | 0.284 |
Peak LA strain | −14.1 ± 2.9 | −17.3 ± 5.0 | 0.297 |
Peak RA strain | −15.8 ± 5.6 | −14.2 ± 5.4 | 0.105 |
Note: Paired t‐test were used for changes in parameters of echocardiography and MRI before and after treatment with SGLT2 inhibitor.
Abbreviations: GCS, global circumferential strain; GLS, global longitudinal strain; GRS, global radial strain; LA, left atrium; LA, left atrial; LV, left ventricular; LVEF, left ventricular ejection fraction; LVDd, left ventricular diameter at end‐diastole; LVEDVi, left ventricular end‐diastolic volume index; LVESi, left ventricular end‐systolic volume index; RA, right atrial; RVFAC, right ventricular fractional area change; TAPSE, tricuspid annular plane systolic excursion; TRPG, tricuspid regurgitation peak gradient.