Table 3.
Intra-Day and Inter-Day Accuracy and Precision of Quality Control Samples for Quantitation of Nemonoxacin in Rat Plasma and Bile (n = 6)
| Plasma | Intra-day | Inter-day | ||||
|---|---|---|---|---|---|---|
| Cnominal (ng/mL) | Cest (ng/mL) | C.V. (%) | Error (%) | Cest (ng/mL) | C.V. (%) | Error (%) |
| 5 | 5.3 | 2.2 | 6.9 | 5.2 | 6.4 | 4.6 |
| 10 | 10.4 | 5.5 | 4.0 | 10.2 | 7.3 | 1.7 |
| 250 | 259 | 6.0 | 3.6 | 244 | 9.0 | −2.3 |
| 2000 | 2152 | 2.2 | 7.6 | 2136 | 1.9 | 6.8 |
| Bile | Intra-day | Inter-day | ||||
| Cnominal (μg/mL) | Cest (μg/mL) | C.V. (%) | Error (%) | Cest (μg/mL) | C.V. (%) | Error (%) |
| 0.1 | 0.1 | 2.6 | 0.4 | 0.1 | 3.2 | 2.1 |
| 5 | 5.2 | 2.3 | 3.1 | 5.1 | 3.1 | 1.9 |
Abbreviation: Cest, estimated concentration.