Figure 6.

Validation by random forest analyses identified highest importance for similar biomarkers, alongside rhythm at baseline and AF pattern, as predictors of sinus rhythm at 12-month follow-up (A—importance, B—SHAP value). AF, atrial fibrillation; ANGPT2, angiopoietin 2; BL, baseline; BMI, body mass index; BMP10, bone morphogenetic protein 10; CA125, cancer antigen 125; CRP, C-reactive protein; D-dimer, ESM1, endothelial specific molecule 1; FABP3, fatty acid binding protein 3; FGF23, fibroblast growth factor 23; GDF15, growth differentiation factor 15; IGFBP7, insulin-like growth factor binding protein 7; IL-6, interleukin-6; MERF, mixed effect random forest; NT-proBNP, N-terminal pro-B-type natriuretic peptide; TnT, cardiac troponin; sCr, serum creatinine; SHAP, SHapley Additive exPlanations