Table 2.

Lung cancer and biomarkers Mendelian randomization study results.

Lung cancer	Biomarker	β	P	FDR	OR	OR (95% CI)
Small cell lung cancer	Creatinine	0.022	0.002	0.018*	1.023	1.008	1.037
	eGFR	-0.022	0.003	0.027*	0.978	0.964	0.992
	Cystatin C	0.026	0.005	0.045*	1.026	1.008	1.045
	Glycated Haemoglobin HbA1c	0.013	0.014	0.028*	1.014	1.003	1.025
	Gamma Glutamyltransferase	-0.013	0.019	0.152	0.987	0.977	0.998
	AST/ALT	0.021	0.022	0.176	1.021	1.003	1.039
Non-small cell lung cancer	Albumin	-0.024	0.002	0.016*	0.977	0.963	0.992
	Cystatin C	0.022	0.006	0.054	1.023	1.006	1.039
	Phosphate	-0.013	0.008	0.072	0.987	0.978	0.997
	Urinary Potassium	-0.011	0.012	0.108	0.990	0.981	0.998
	C Reactive Protein	0.013	0.04	0.28	0.025	1.013	1.001
Lung squamous cell carcinoma	eGFR	-0.022	9.58×10-6	8.62×10-5*	0.979	0.969	0.988
	Creatinine	0.021	1.16×10-5	1.05×10-3*	1.021	1.010	1.031
	Cystatin C	0.028	0.004	0.036*	1.029	1.009	1.049
	Urate	0.012	0.020	0.180*	1.012	1.002	1.022
	SHBG	-0.020	0.036	0.108	0.981	0.963	0.999
	Urea	0.010	0.046	0.141	1.010	1.000	1.019
	Glycated Haemoglobin HbA1c	0.019	0.049	0.098	1.019	1.000	1.038
Lung adenocarcinoma	Alkaline Phosphatase	0.015	0.011	0.033*	1.015	1.003	1.027

*FDR:P<0.05.