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. 2024 Dec 2;14:1453246. doi: 10.3389/fonc.2024.1453246

Table 3.

Results of bidirectional Mendelian randomization study on lung cancer and biomarkers (FDR < 0.05).

Biomarkers/lung cancer Biomarkers/Lung cancer β P FDR OR OR (95% CI)
Urate Non-Small Cell Lung Cancer -0.158 0.004* 0.036* 0.854 0.766 0.952
Small cell lung cancer Creatinine 0.022 0.002* 0.018* 1.023 1.008 1.037
eGFR -0.022 0.003* 0.027* 0.978 0.964 0.992
Cystatin C 0.026 0.005* 0.045* 1.026 1.008 1.045
Glycated Haemoglobin HbA1c 0.013 0.014* 0.028* 1.014 1.003 1.025
Non-small cell lung cancer Albumin -0.024 0.002* 0.016* 0.977 0.963 0.992
Lung squamous cell carcinoma eGFR -0.022 9.58×10-6* 8.62×10-5* 0.979 0.969 0.988
Creatinine 0.021 1.16×10-5* 1.05×10-3* 1.021 1.01 1.031
Cystatin C 0.028 0.004* 0.036* 1.029 1.009 1.049
Lung adenocarcinoma Alkaline Phosphatase 0.015 0.011* 0.033* 1.015 1.003 1.027

*P<0.05.