Table 4.
Univariate and multivariate Cox proportional hazards analysis of factors associated with recurrence.
| Characteristics | Univariate Cox analysis | Multivariable Cox analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Age | 1.005 (0.983–1.028) | 0.678 | – | – |
| Gender | 1 (0.507–1.974) | 0.999 | – | – |
| HBsAg | 1.503 (0.646–3.495) | 0.344 | – | – |
| AFP group | 1.133 (0.664–1.932) | 0.648 | – | – |
| ALT group | 1.017 (0.616–1.677) | 0.948 | – | – |
| Child–Pugh class | 16.040 (3.214–80.090) | <0.001* | 10.375 (1.983–54.276) | 0.006* |
| Tumor size group | 1.143 (0.685–1.909) | 0.608 | – | – |
| Tumor number | 2.607 (1.545–4.400) | <0.001* | 3.183 (1.817–5.576) | <0.001* |
| Vascular invasion | 3.487 (1.754–6.935) | <0.001* | 4.519 (2.200–9.285) | <0.001* |
| BCLC stage | 2.433 (1.465–4.042) | <0.001* | – | – |
| iMRS | 2.311 (1.144–4.672) | 0.020* | 3.321 (1.579–6.986) | 0.002* |
HBsAg, hepatitis B surface antigen; AFP, α-fetoprotein; ALT, alanine aminotransferase; BCLC, Barcelona Clinic Liver Cancer; HR, hazard ratio; CI, confidence interval.
Characteristics with a p < 0.05 are displayed in bold.