Table 3.
Epithelial thickness repeatability in normal and corneal diseased eyes
| Sector | Normal eye | Corneal disease eye | ICC difference | 95% CI* | ||||
|---|---|---|---|---|---|---|---|---|
|
|
|
|||||||
| ICC | Sw (μm) | CoV (%) | ICC | Sw (μm) | CoV (%) | |||
| 0–2 mm | 0.918 | 0.827 | 2.214 | 0.939 | 1.298 | 5.993 | 0.021 | −0.031 to 0.098 |
| 2–5 mm | ||||||||
| S | 0.819 | 1.148 | 3.808 | 0.874 | 1.740 | 6.533 | 0.055 | −0.037 to 0.182 |
| SN | 0.918 | 0.971 | 2.727 | 0.906 | 1.453 | 5.002 | −0.012 | −0.066 to 0.069 |
| N | 0.942 | 0.805 | 2.173 | 0.932 | 1.464 | 4.420 | −0.010 | −0.047 to 0.046 |
| IN | 0.857 | 1.035 | 2.947 | 0.917 | 1.545 | 5.502 | 0.060 | −0.019 to 0.220 |
| I | 0.795 | 1.092 | 3.481 | 0.897 | 1.694 | 6.362 | 0.102 | −0.018 to 0.285 |
| IT | 0.892 | 1.035 | 2.641 | 0.889 | 1.612 | 7.668 | −0.003 | −0.101 to 0.093 |
| T | 0.923 | 0.941 | 2.575 | 0.912 | 1.542 | 5.317 | −0.011 | −0.056 to 0.054 |
| ST | 0.856 | 1.080 | 3.431 | 0.885 | 1.649 | 5.721 | 0.029 | −0.052 to 0.160 |
| 5–7 mm | ||||||||
| S | 0.818 | 1.369 | 4.921 | 0.810 | 2.043 | 9.522 | −0.008 | −0.134 to 0.141 |
| SN | 0.855 | 1.291 | 4.129 | 0.796 | 1.805 | 6.668 | −0.059 | −0.158 to 0.069 |
| N | 0.949 | 0.760 | 2.160 | 0.919 | 1.397 | 4.167 | −0.030 | −0.073 to 0.014 |
| IN | 0.891 | 1.027 | 2.928 | 0.882 | 1.701 | 6.027 | −0.009 | −0.117 to 0.140 |
| I | 0.794 | 1.371 | 4.223 | 0.855 | 1.808 | 7.306 | 0.061 | −0.087 to 0.236 |
| IT | 0.891 | 1.047 | 2.853 | 0.823 | 1.849 | 8.439 | −0.068 | −0.199 to 0.036 |
| T | 0.931 | 0.900 | 2.589 | 0.862 | 1.691 | 6.308 | −0.069 | −0.127 to −0.008† |
| ST | 0.796 | 1.326 | 4.982 | 0.815 | 1.841 | 7.942 | 0.019 | −0.118 to 0.186 |
| 7–9 mm | ||||||||
| S | 0.694 | 1.760 | 6.695 | 0.775 | 1.975 | 7.765 | 0.081 | −0.146 to 0.285 |
| SN | 0.789 | 1.653 | 5.134 | 0.669 | 2.762 | 14.120 | −0.120 | −0.291 to 0.073 |
| N | 0.942 | 0.979 | 2.821 | 0.842 | 1.794 | 6.392 | −0.100 | −0.175 to −0.031† |
| IN | 0.768 | 2.001 | 5.292 | 0.644 | 3.241 | 11.760 | −0.124 | −0.252 to 0.115 |
| I | 0.916 | 1.239 | 3.262 | 0.860 | 2.077 | 6.427 | −0.056 | −0.157 to 0.012 |
| IT | 0.551 | 2.283 | 6.406 | 0.586 | 3.340 | 13.360 | 0.035 | −0.266 to 0.258 |
| T | 0.919 | 1.017 | 3.005 | 0.810 | 1.869 | 7.553 | −0.109 | −0.189 to −0.016† |
| ST | 0.762 | 1.632 | 5.148 | 0.768 | 2.009 | 9.606 | 0.006 | −0.180 to 0.232 |
ICC = intraclass correlation coefficient; CI = confidence interval; Sw = within-subject standard deviation; CoV = coefficient of variation; S = superior; SN = superior nasal; N = nasal; IN = inferior nasal; I = inferior; IT = inferior temporal; T = temporal; ST = superior temporal.
*
The 95% CI of ICC difference was obtained from 1,000 resampling by bootstrap methods;
†
The 95% CI that does not include 0, was considered as statistically significant.