Table 4.
Likelihood of 12-month survival and favorable outcome based on ICP peak times.
| Unadjusted odds ratio (OR) (95%CI) | Adjusted odds ratio (OR)b (95%CI) | |
|---|---|---|
| 12-month survival | ||
| First day of maximum average ICP (0–7) | 1.0 (0.9–1.1) | 1.0 (0.9–1.1) |
| Early (day 0–1) intermediate (day 2–3) or late (day 4–7) ICP peak | 1.0 (0.8–1.2) | 1.1 (0.9–1.5) |
| Very early (day 0) ICP peak versus later peak | 0.5 (0.3–0.8)a | 0.6 (0.3–1.1) |
| Very late (day 7) ICP peak versus earlier peak | 0.4 (0.2–1.0)a | 0.4 (0.2–1.1) |
| Average ICP peak on third day versus other peak moments | 0.9 (0.5–1.4) | 1.0 (0.5–1.9) |
| ICP >20 at any timepoint | 0.4 (0.2–0.5)a | 0.3 (0.2–0.4)a |
| 12-month favorable outcome | ||
| First day of maximum average ICP (0–7) | 0.9 (0.8–1.0) | 0.9 (0.8–1.0) |
| Early (day 0–1) intermediate (day 2–3) or late (day 4–7) ICP peak | 0.8 (0.7–0.9)a | 0.9 (0.7–1.1) |
| Very early (day 0) ICP peak versus later peak | 1.0 (0.7–1.6) | 1.4 (0.8–2.4) |
| Very late (day 7) ICP peak versus earlier peak | 0.3 (0.1–0.8)a | 0.3 (0.1–1.0) |
| Average ICP peak on third day versus other peak moments | 1.2 (0.8–1.9) | 1.2 (0.7–2.1) |
| ICP >20 at any timepoint | 0.6 (0.5–0.9)a | 0.5 (0.4–0.8)a |
Abbreviations: ICP, intracranial pressure; OR, odds ratio.
a
Statistically significant (p ≤ 0.05).
b
The odds ratio was adjusted for age, baseline GCS, pupillary reactivity, the day of maximum TIL, the occurrence of emergency intracranial surgery and polytrauma requiring extracranial surgery.