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. 2025 Jan 1;25(1):155–164. doi: 10.17305/bb.2024.10944

Figure 1.

Figure 1.

Circ_0023179 was highly expressed in NSCLC. (A) Schematic diagram of the structure of circ_0023179; (B) qRT-PCR was used to detect the expression of circ_0023179 in NSCLC tissues and paraneoplastic tissues; (C) qRT-PCR was used to detect the expression of circ_0023179 in HBE cells and four NSCLC cell lines (A549, H520, H1299, and H1975); (D and E) qRT-PCR was used to detect circ_0023179 and LRP5 in A549 and H1299 cells treated with RNase R; (F and G) qRT-PCR was used to detect circ_0023179 and LRP5 in A549 and H1299 cells treated with actinomycin D; (H and I) Nucleic acid electrophoresis was used to verify the PCR products of the cDNA and gDNA transcripts of circ_0023179. *P < 0.05, **P < 0.01, ***P < 0.001. NSCLC: Non-small-cell lung cancer; qRT-PCR: Quantitative real-time polymerase chain reaction; HBE: Human bronchial epithelial; cDNA: Complementary DNA.