Fig. 3.

Cosinor-based rhythmometry analysis of peripheral blood mononuclear cells on the study population (n = 68). Results are presented as percentage of immune cells. The panels include patients with active CS (red, n = 34) in remission (green, n = 10) compared to controls (grey, n = 34). Dots are single measurements for each time point. Curves are obtained from the pooled data. Results are presented as percentages of immune subsets over whole PBMCs (a, b), lymphocytes (c, g, h), monocytes (d, e, f) and NK cells (i). p values for comparisons of cosinor-based rhythmometry parameters are available in Table 3.