Table 1.
Baseline characteristics of the study cohort.
| Patients with CS (n = 34) | Controls (n = 34) | pa | |
|---|---|---|---|
| Age (years) | 47.4 (43.8–51.2) | 42.4 (37.6–47.9) | 0.111 |
| Sex (F/M) | 23/11 | 20/14 | 0.204 |
| BMI (kg/m2) | 27.97 (26.15–29.96) | 23.64 (22.56–24.69) | 0.004 |
| Waist circumference (cm) | 99.4 (94.8–104.8) | 77.2 (74.0–80.2) | <0.001 |
| Systolic (mmHg) | 133 (125–140) | 117 (113–120) | 0.001 |
| Diastolic (mmHg) | 83 (79–87) | 76 (73–79) | 0.011 |
| Aetiology of CS | |||
| Pituitary CS n (%) | 18 (52.9) | ||
| Adrenal CS n (%) | 13 (38.2) | ||
| Ectopic CS n (%) | 3 (8.8) | ||
| Comorbidities | |||
| Hypertension n (%) | 23 (67.6) | ||
| Diabetes n (%) | 13 (38.2) | ||
| Dyslipidaemia n (%) | 21 (61.8) | ||
| Osteoporosis n (%) | 9 (26.5) | ||
| Hypercoagulability n (%) | 11 (32.4) | ||
| Biochemistry | |||
| Glycaemia (mg/dL) | 85.27 (80.56–90.83) | 85.77 (83.33–88.57) | 0.864 |
| HbA1c (%) | 5.90 (5.62–6.23) | 5.27 (5.17–5.40) | 0.006 |
| Total cholesterol (mg/dL) | 203 (188–217) | 186 (174–200) | 0.101 |
| HDL cholesterol (mg/dL) | 62 (56–67) | 62 (56–68) | 0.988 |
| LDL cholesterol (mg/dL) | 120 (109–132) | 106 (96–116) | 0.086 |
| Triglycerides (mg/dL) | 114 (100–127) | 92 (77–108) | 0.043 |
Values are expressed as mean (lower-upper limit of 95% CI), median (25th–75th percentile), or percentages (%) as appropriate. n = 34 for active CS and n = 34 for controls for each variable except for systolic and diastolic blood pressure (n = 32 for CS) and HbA1c% (n = 30 for CS and n = 28 for controls).
a
p value for Mann–Whitney test.