Table 1.
Clinical goals per fraction are shown for the clinical target volume cropped 5 mm from the body contour (CTV-05), planning target volume cropped 5 mm from the body contour (PTV-05) , right lung, left breast, and heart. Abbreviations: DXX = minimum dose delivered to XX of the volume, Dmean = mean dose in the volume, VX Gy = percentage of volume recieving atleast X Gy.
| Target | CTV-05 D98% (%,) | PTV-05 D98% (%,) | PTV-05 D2% (%) | PTV-05 D0.1 cm3 (%) | PTV-05 Dmean (%) |
|---|---|---|---|---|---|
| Clinical goal | ≥95 (not in template) | ≥95 | ≤107 | ≤112 (≤aim 107%) | ≥99 and ≤101% |
| TPR | 96.7 (96.2-96.9) | 95.6 (95.0—95.9) | 103.7 (103.2—104.3) | 107.5 (105.5—112.9) | 100.1 (99.2—100.6) |
| TPS | 96.2* (89.6—97.5) | 93.8* (76.8—96.2) | 104.0* (103.1—107.5) | 108.1* (105.2—113.8) | 99.7* (97.7—101.0) |
| TPA | 96.7* (96.2—97.5) | 95.7* (95.1—96.0) | 103.7* (102.9—104.7) | 107.1* (105.5—115.6) | 100.1* (99.0—100.7) |
| OARs | Lung right V5 Gy (%) | Lung right V20 Gy (%) | Breast left Dmean (cGy) | Heart Dmean (cGy) | Lungs Dmean (cGy) |
| Clinical goal | ≤20 | ≤10 | ≤20 | ≤16 | ≤60 |
| TPR | 18 (9—27) | 4 (1—10) | 3 (2—6) | 7 (6—14) | 37 (22—69) |
| TPS | 17 (7—27) | 4 (0.2—18) | 3 (2—6) | 7 (5—9) | 37 (21—69) |
| TPA | 17 (8—29) | 4 (0.3—11) | 3 (2—8) | 7 (5—14) | 37 (25—72) |
Median dose (range) is shown for TPR (pretreatment), TPS (pretreatment plan on daily anatomy), and TPA (new treatment plan on daily anatomy). The dose from the 3 cone beam computed tomographies was not included in the presented data.
Abbreviations: CTV = clinical target volume; Gy = gray (J/kg); OAR = organ at risk; PTV = planning target volume; TPA = adaptive treatment plan; TPR = reference treatment plan; TPS = scheduled treatment plan.
Significant difference (P < .05) between TPS and TPA.