Table 1.
Subject demographics.
| Controls (N=17) | BAV (N=35) | CoA-BAV (N=18) | p | |
|---|---|---|---|---|
| Female (%) | 8 (47) | 9 (26) | 4 (22) | |
| Age at scan (y) | 13.6 ± 3.2 | 15.0 ± 3.5 | 15.4 ± 2.6 | 0.20 |
| Height (m) | 1.57 ± 0.15 | 1.57 ± 0.21 | 1.67 ± 0.14 | 0.20 |
| Weight (kg) | 56.0 ± 22.0 | 52.0 ± 19.1 | 64.1 ± 21.5 | 0.14 |
| BSA (m2) | 1.5 ± 0.4 | 1.5 ± 0.4 | 1.7 ± 0.3 | 0.19 |
| Valve phenotype N (RL/RN/LN/unicuspid) | - | 21/9/1/4 | 15/1/0/2 | - |
| Aortic stenosis N (%) | - | 15 (43) | 5 (28) | - |
| Mild | - | 9 (26) | 3 (17) | - |
| Moderate | - | 1 ( 3) | 2 (11) | - |
| Severe | - | 2 ( 6) | 0 ( 0) | - |
| Aortic regurgitation N (%) | - | 15 (43) | 2 (11) | - |
| Mild | - | 13 (37) | 2 (11) | - |
| Moderate | - | 2 ( 6) | 0 ( 0) | - |
| Severe | - | 0 ( 0) | 0 ( 0) | - |
| Aortic Z-scores (measured on PCMRA) | ||||
| STJ | −0.8 ± 1.1 | 1.5 ± 1.4 | 0.5 ± 1.4 | <0.001 |
| Mid-AAo | 0.8 ± 1.0 | 3.5 ± 1.5 | 2.3 ± 1.2 | <0.001 |
| Distal-AAo | 0.7 ± 1.5 | 2.1 ± 1.4 | 0.8 ± 1.3 | <0.001 |
BAV bicuspid aortic valve, CoA coarctation, BSA body surface area, RL right-left coronary cusp fusion, RN right-noncoronary cusp fusion, LN left-noncoronary cusp fusion, PCMRA phase-contrast magnetic resonance angiography, STJ sinotubular junction, AAo ascending aorta
Data are numbers (%) of cases or mean ± standard deviation. Statistical significance is shown by bold numbers