TABLE 1.
Characteristic | Discovery cohort | Validation cohort |
---|---|---|
No. of patients (%) | ||
Age > 70 years | 14 (47) | 11 (36) |
Male sex | 19 (63) | 22 (73) |
Karnofsky performance status >60 | 7 (23) | 17 (56) |
Elevated lactate dehydrogenase | 14 (47) | 20/29 (69) |
Deep brain lesions | 22 (73) | 14/30 (47) |
Altered mentation | 19 (63) | 9/30 (30) |
Frontline treatment | ||
HDMTX‐based chemotherapy | 28 (93) | 28 (93) |
Others | 2 (7) | 2 (7) |
Non‐GCB (Hans algorithm) | 24 (80) | 25 (83) |