Table 1. IC₅₀ values (μM)^a Obtained for Cancer Cells Treated with the Investigated Ru Complexes in the Dark or after Irradiation as Determined by the MTT Assay^b.

	Dark	Blue	PTIBlue	Red	PTIRed
HeLa
RuL1	2.0 ± 0.3	0.12 ± 0.02	16.6	0.27 ± 0.07	7.4
RuL2	1.9 ± 0.4	0.06 ± 0.01	31.6	0.13 ± 0.03	14.6
RuL3	2.5 ± 0.2	0.033 ± 0.006	75.8	0.14 ± 0.01	19.2
A375
RuL1	1.3 ± 0.2	0.05 ± 0.01	26.0	0.11 ± 0.02	11.8
RuL2	1.2 ± 0.2	0.023 ± 0.003	52.2	0.07 ± 0.02	17.1
RuL3	1.3 ± 0.2	0.022 ± 0.004	59.0	0.06 ± 0.02	21.7
HCT116
RuL1	0.9 ± 0.2	0.045 ± 0.005	20	0.15 ± 0.02	6
RuL2	0.8 ± 0.1	0.008 ± 0.002	100	0.08 ± 0.01	10
RuL3	1.08 ± 0.09	0.013 ± 0.001	83.1	0.06 ± 0.01	18

^aData represent mean ± SD from at least 3 independent experiments, each performed in triplicate.

^bPTI (Phototoxicity index) was calculated using the following formula: PTI_(Blue,Red) = IC₅₀ (dark-nonirradiated cells)/IC₅₀ (irradiated cells; Blue, Red).