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. 2024 Dec 2;67(23):21470–21485. doi: 10.1021/acs.jmedchem.4c02357

Table 2. IC50 Values (μM)a Obtained for Noncancerous MRC5pd30 Cells Treated with the Investigated Ru Complexes in the Dark as Determined by the MTT Assay.

  MRC5pd30 SIb
RuL1 12 ± 4 8.6
RuL2 7 ± 1 5.4
RuL3 9.3 ± 0.9 5.7
a

Data represent mean ± SD from 3 independent experiments performed in triplicate.

b

SI (selectivity index) was calculated using the following formula: SI= IC50 (MRC5pd30, dark)/average IC50 (cancer cells, dark).