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. 2024 Nov 30;67(23):21486–21504. doi: 10.1021/acs.jmedchem.4c02366

Table 5. Pharmacokinetic Properties of Select Analogs in Mice.

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a

Compounds were administered at 10 mg kg–1 of body weight by oral gavage to C57BL/6 male mice. Plasma samples were collected over 24 h after gavage and analyzed by LC-MS/MS. Cmax = maximum plasma concentration. t1/2 = half-life.