TABLE 1.
Clinical data and predicted molecular subtypes of ependymoma by predicted sex in Pajtler and COG MCI.
| Pajtler | N = 492 | Male, N = 302 | Female, N = 190 |
|---|---|---|---|
| Predicted subtypes, n (%) | |||
| PF‐EPN‐A | 238 | 154 (65) | 84 (35) |
| PF‐EPN‐B | 52 | 21 (40) | 31 (60) |
| PF‐SE | 34 | 26 (76) | 8 (24) |
| SP‐EPN | 21 | 13 (62) | 8 (38) |
| SP‐MPE | 26 | 14 (54) | 12 (46) |
| ST‐EPN‐RELA | 87 | 56 (64) | 31 (36) |
| ST‐EPN‐YAP1 | 13 | 3 (23) | 10 (77) |
| ST‐SE | 21 | 15 (71) | 6 (29) |
| Vital status, n (%) | |||
| Alive | 273 | 154 (56) | 119 (44) |
| Death | 83 | 56 (67) | 27 (33) |
| Missing | 136 | 92 | 44 |
| Progression, n (%) | |||
| Not progression | 168 | 87 (52) | 81 (48) |
| Progression | 198 | 127 (64) | 71 (36) |
| Missing | 126 | 88 | 38 |
| COG MCI | N = 103 | Male, N = 58 | Female, N = 45 |
| Predicted subtypes, n (%) | |||
| PF‐EPN‐A | 45 | 23 (51) | 22 (49) |
| PF‐EPN‐B | 34 | 24 (71) | 10 (29) |
| SP‐MPE | 14 | 5 (36) | 9 (64) |
| ST‐EPN‐RELA | 10 | 6 (60) | 4 (40) |
Note: One case diagnosed with astrocytoma was excluded. Distributions of molecular subtypes of ependymoma in Pajtler and COG APEC14B1‐MCI were statistically significantly different by sex according to Fisher's exact test for count data with simulated p value (based on 2000 replicates).