Table 2.

3D bioprinted tumor models (Abbreviations: PEG‐DMA PEG‐dimethacrylate; GelMA methacrylated gelatin; PLGA poly(lactic‐co‐glycolic) acid; PEVA A poly(ethylene‐co‐vinyl acetate); NA not applicable

3D bioprinted model	Tumor model type	Cell type	Scaffold	Bioprinting modality	Printing structure	Printing substrate	Refs.
Tumoroids	Breast	MCF‐7	Sacrificial gelatin and PEG‐DMA	EBB	Concave structure	Petri‐dish	[103]
	Breast	BT474	PEG‐MA	SLB	Concave structure	Glass‐cover slip	[104]
	Breast	MDA‐MB‐231	Alginate/Chitosan	LBB	Microbeads	Petri‐dish/Glass bottom chamber plates	[45]
	Pancreatic cancer	AR42J‐B‐13	GelMA	LBB	Microdroplet	Glass slides	[105]
	Neuroblastoma, Lung cancer and Glioblastoma	SK‐N‐BE(2), H460 & U87vIII	Alginate	DBB	Cup structure	Multi‐well plate	[106]
	Liver & colorectal cancers	HepG2 & Caco2	HA/Collagen and gelatin bath	EBB	Immersion into a gelatin bath	Multi‐well plate	[107]
	Cervical cancer	HeLa	gelatin/alginate/fibrinogen	EBB	A grid structure	Petri‐dish	[108]
Co‐culture tumor models	Ovarian cancer	OVCAR5 & MRC5	Matrigel for pre‐coating petri‐dish	EBB	Two droplets of OVCAR5 (ovarian cancer) and MRC5 fibroblasts on Matrigel coated wells	Petri‐dish	[111]
	Liver Cancer	HepG2 and/or HUVEC	PEG‐DA/GelMA	Digital Light‐based	Constructs of varying spatial geometries	Multi‐well plate	[112]
	Glioblastoma	U87 & HUVEC	Decellularized ECM	EBB	Tumor on‐a‐chip	Chamber	[88]
	Glioblastoma	RAW264.6 & GL261	GelMA	EBB	Mini‐brain (Two‐step printing)	Glass slide	[115]
	Glioblastoma	TS576 (Glioblastoma patient derived cell line) & HUVEC	PEG‐HA & GelMA	SLB	A tumor region surrounded by a donut‐shape acellular ECM region. HUVEC cell layer encompass the ring	Glass slide	[114]
	Glioblastoma/Vasculature model	HUVEC, U87 & fibroblasts	Gelatin/Alginate/Fibrinogen	EBB	A cuboidal shape	Petri‐dish	[119]
	Pancreatic cancer/metastatic model	Primary human pancreatic tumor cells, fibroblasts and preadipocytes & HUVEC	Alginate as a sacrificial scaffold	EBB	Scaffold‐free tissue models to study metastasis	Transwell membrane	[116]
	Glioma	Human neural progenitor cells & U118	NA	Kenzen, micro‐needling	Needle array	Needle array	[117]
	Melanoma & Gastric cancer/Vasculature model	SK‐MEL‐28 &HTB‐103	Decellularized ECM	EBB	Cell droplets into PEVA structure & perfusable vessel	Chamber	[87]
	Lung cancer/Vasculature and metastatic model	A549 & HUVEC	Fibrin and GelMA/PLGA	EBB	Tumor cell droplet/perfusable vessel onto a fibroblast‐laden fibrin gel; Core/shell structured capsules with growth factors	Chamber	[120]
	Glioblastoma/vasculature and metastatic model	Patient‐derived glioblastoma cells, astrocytes, microglia, primary human microvascular brain pericytes & HUVEC	Fibrinogen/Gelatin and Pluronic F127	EBB	Tumor compartment (Fibrin bioink with glioblastoma cells and stromal cell)s; Perfusable vessels on top of the fibrin bioinks	A thin coverslip, framed by a polydimethylsiloxane gasket	[121]