Table 2.
Comparative Analysis of the Discrimination of Each Systemic Inflammation-Related Biomarkers for All-Cause and CVD Mortality in PD Patients
| Discrimination ability | All-Cause Mortality | CVD Mortality | ||||
|---|---|---|---|---|---|---|
| C-Statistic | Difference | p | C-Statistic | Difference | p | |
| IBI | 0.619 (0.597,0.642) | Ref | 0.621 (0.594,0.648) | Ref | ||
| CALLY | 0.614 (0.592,0.637) | −0.003 (−0.011,-0.004) | <0.001 | 0.612 (0.585,0.640) | −0.007 (−0.016,0.003) | 0.155 |
| LCR | 0.606 (0.584,0.629) | −0.011 (−0.018,-0.004) | 0.002 | 0.608 (0.580,0.635) | −0.011 (−0.020,-0.003) | 0.011 |
| NC | 0.603 (0.581,0.625) | −0.017 (−0.025,-0.008) | <0.001 | 0.596 (0.569,0.623) | −0.025 (−0.036,-0.014) | <0.001 |
| CAR | 0.601 (0.579,0.624) | −0.018 (−0.029,-0.007) | 0.001 | 0.590 (0.562,0.617) | −0.031 (−0.045,-0.017) | <0.001 |
| PC | 0.599 (0.577,0.621) | −0.021 (−0.033,-0.009) | 0.001 | 0.590 (0.563,0.617) | −0.031 (−0.047,-0.015) | <0.001 |
| SIRI | 0.593(0.570,0.616) | −0.026 (−0.052,-0.001) | 0.041 | 0.590 (0.562,0.619) | −0.031 (−0.061,0.000) | 0.051 |
| SII | 0.590 (0.567,0.614) | −0.029 (−0.055,-0.004) | 0.026 | 0.603 (0.574,0.631) | −0.018 (−0.048,0.12) | 0.245 |
| NAR | 0.588 (0.565,0.611) | −0.031 (−0.057,-0.006) | 0.016 | 0.574 (0.546,0.602) | −0.047 (−0.078,-0.016) | 0.003 |
| NLR | 0.579 (0.556,0.602) | −0.040 (−0.064,-0.017) | 0.001 | 0.603 (0.574,0.632) | −0.018 (−0.047,0.011) | 0.225 |
| LA | 0.578 (0.555,0.601) | −0.042 (−0.068,-0.015) | 0.002 | 0.595 (0.567,0.623) | −0.026 (−0.058,0.007) | 0.118 |
| MLR | 0.577 (0.553,0.600) | −0.043 (−0.071,-0.015) | 0.002 | 0.573 (0.544,0.602) | −0.047 (−0.081,-0.013) | 0.006 |
| PAR | 0.574 (0.551,0.598) | −0.045 (−0.077,-0.013) | 0.005 | 0.556 (0.526,0.586) | −0.065 (−0.104,-0.026) | 0.001 |
| PLR | 0.571 (0.548,0.594) | −0.049 (−0.076,-0.021) | 0.001 | 0.594 (0.566,0.622) | −0.027 (−0.060,0.007) | 0.119 |
| GLR | 0.570 (0.547,0.593) | −0.049 (−0.079,-0.020) | 0.001 | 0.591 (0.563,0.619) | −0.030 (−0.065,0.006) | 0.101 |
| NP | 0.568 (0.545,0.591) | −0.051 (−0.080,-0.023) | <0.001 | 0.560 (0.531,0.589) | −0.061 (−0.095,-0.026) | 0.001 |
| PDWLR | 0.556 (0.528,0.585) | −0.075 (−0.108,-0.042) | <0.001 | 0.580 (0.545,0.615) | −0.045 (−0.087,-0.004) | 0.034 |
| PNR | 0.526 (0.503,0.549) | −0.094 (−.012,-0.067) | <0.001 | 0.526 (0.497,0.555) | −0.095 (−0.129,-0.061) | <0.001 |
| PDWPCR | 0.518 (0.489,0.546) | −0.113 (−0.154,-0.073) | <0.001 | 0.503 (0.467,0.540) | −0.121 (−0.172,-0.071) | <0.001 |
Abbreviations: IBI, inflammatory burden index (C-reactive protein–neutrophil–lymphocyte ratio); CALLY, C-reactive protein-albumin-lymphocyte index; LCR, Lymphocyte-to-C-reactive protein ratio; NC, Lymphocyte C-reactive protein score; CAR, C-reactive protein-to-albumin ratio; PC, Platelet-C-reactive protein score; SIRI, Systemic inflammation response index; SII, Systemic-immune-inflammation index; NAR, Neutrophil-to-albumin ratio; NLR, Neutrophil-to-lymphocyte ratio; LA, Lymphocyte–albumin score; MLR, Monocyte-to-lymphocyte Ratio; PAR, Platelet-to-albumin ratio; PLR, Platelet-to-lymphocyte ratio; GLR, Glucose to lymphocyte Ratio; NP, Neutrophil–platelet score; PDWLR, Platelet distribution width to lymphocyte ratio; PNR, Platelet-to-Neutrophil Ratio; PDWPCR, Platelet distribution width to platelet count ratio.