Table 5.

Associations of IBI and IBI Categories with All-Cause and CVD Mortality. (Cox Regression Analysis)

	Model 1	p value	Model 2	p value	Model 3	p value
All-cause mortality
Continuous (per SD)	1.203(1.169,1.239)	<0.001	1.158(1.121,1.196)	<0.001	1.155(1.113,1.198)	<0.001
Cut-off value
C1(<50)	Ref		Ref		Ref
C2(≥50)	2.132(1.1.825,2.492)	<0.001	1.775(1.514,2.079)	<0.001	1.724(1.455,2.042)	<0.001
Quartiles
Q1(<4.99)	Ref		Ref		Ref
Q2(4.99–13.95)	1.277(1.022,1.595)	0.315	1.184 (0.947,1.480)	0.139	1.133 (0.897,1.431)	0.296
Q3(13.95–34.12)	1.624(1.312,2.010)	0.001	1.466 (1.183,1.817)	<0.001	1.412 (1.129,1.767)	0.003
Q4(>34.12)	2.438(1.995,2.980)	<0.001	1.869 (1.524,2.293)	<0.001	1.676 (1.350,2.081)	<0.001
CVD mortality
Continuous (per SD)	1.216(1.173,1.261)	<0.001	1.164(1.119,1.211)	<0.001	1.175(1.122,1.230)	<0.001
Cut-off value
C1(<50)	Ref		Ref		Ref
C2(≥50)	2.301(1.876,2.823)	<0.001	1.915(1.555,2.358)	<0.001	1.887(1.512,2.357)	<0.001
Quartiles
Q1(<4.99)	Ref		Ref		Ref
Q2(4.99–13.95)	1.334(0.981,1.013)	0.066	1.235 (0.907,1.680)	0.18	1.228 (0.890,1.694)	0.211
Q3(13.95–34.12)	1.888(1.414,2.520)	<0.001	1.714 (1.283,2.291)	<0.001	1.670 (1.232,2.265)	0.001
Q4(>34.12)	2.605(1.976,3.434)	<0.001	2.036 (1.538,2.696)	<0.001	1.884 (1.398,2.538)	<0.001

Notes: Model 1: unadjusted. Model 2: adjusted for age, sex, BMI, systolic pressure, diastolic pressure, DM, and CVD history. Model 3: Model 2 plus smoking, alcohol consumption, medication (CCB, ACEI, ARB, β-blocker, ɑ-blocker, Diuretic, Aspirin), PLT, HB, UA, ALB, TC, TG, calcium, phosphorus, iPTH, eGFR and Kt/V.

Abbreviations: IBI, inflammatory burden index; BMI, body mass index; DM,diabetes; CVD, cardiovascular disease; CCB, calcium channel blocker; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; PLT, platelet; HB, hemoglobin; UA, Uric acid; ALB, albumin; TC, cholesterol; TG, triglyceride; iPTH, intact Parathyroid hormone; eGFR, estimated glomerular; Kt/V, K dialyzer clearance of urea.