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Aberrant expression of let-7a-5p alters the growth, migration, and invasion of A459 lung cancer cells. (A) CCK8 assays show that let-7a-5p suppresses the growth of A549 lung cancer cells. (B, C) Transwell assays demonstrate that let-7a-5p inhibits the invasion (B) and migration (C) of A549 lung cancer cells. (D, E) Quantitative analysis of (B, C). NC represents the negative control. * p < 0.05 compared with the control group, using the pooled variance t-test.
