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. 2024 Dec 2;21(12):e1004500. doi: 10.1371/journal.pmed.1004500

Table 1. Distribution of latent class membership and care outcomes by race (N = 2,998).

Overall non-black Black Contrast
N = 2,998 N = 1,503 N = 1,495
N (%) N (%) N (%) RFD (95% CI)*
Latent class domains
Socioeconomic status (SES)
High SES 1,100 (37%) 757 (50%) 343 (23%) ref
Moderate SES 726 (24%) 257 (17%) 469 (31%) 14.3 (11.2, 17.3)
 Low SES 1,172 (39%) 489 (33%) 683 (46%) 13.2 (9.7, 16.6)
Care barriers
 Fewer barriers 2,478 (83%) 1,346 (90%) 1,132 (76%) ref
 More barriers 520 (17%) 157 (10%) 363 (24%) 13.8 (11.2, 16.5)
Care use
 Short travel, high use 1,750 (58%) 868 (58%) 882 (59%) ref
 Short travel, low use 415 (14%) 136 (9.0%) 279 (19%) 9.6 (7.2, 12.1)
 Medium travel 551 (18%) 336 (22%) 215 (14%) −8.0 (−10.7, −5.2)
 Variable travel 164 (5.5%) 100 (6.7%) 64 (4.3%) −2.4 (−4.0, −0.7)
 Long travel 118 (3.9%) 63 (4.2%) 55 (3.7%) −0.5 (−1.9, 0.9)
Care outcomes
Diagnosis
Not delayed 2,450 (82%) 1,280 (85%) 1,170 (78%) ref
Delayed 545 (18%) 222 (15%) 323 (22%) 6.9 (4.1, 9.6)
Treatment initiation
Not delayed 1,942 (65%) 1,033 (69%) 909 (61%) ref
Delayed 1,053 (35%) 469 (31%) 584 (39%) 7.9 (4.5, 11.3)
Treatment duration
Not prolonged 1,326 (52%) 681 (54%) 645 (50%) ref
Prolonged 1,242 (48%) 584 (46%) 658 (50%) 4.3 (0.5, 8.2)
Receipt of OncotypeDx
Tested 609 (38%) 401 (43%) 208 (31%) ref
Not tested 1,006 (62%) 537 (57%) 469 (69%) 12.2 (7.3–16.7)

* Relative frequency difference (RFD, expressed as a percentage difference on the absolute scale) and 95% confidence interval, comparing frequencies of latent class domains between black women and non-black women (referent group).

Latent variables were defined for SES (income, education, country of birth, job type, and marital status), care barriers (insurance, urban/rural status, job loss, self-reported financial barriers to care, self-reported transportation barriers to care), and care use (pre-diagnostic regular care, breast cancer screening, mode of initial cancer detection (mammogram vs. noticed lump), and travel (based on estimated driving time) to diagnosis and surgery).

OncotypeDx is a genomic test of breast cancer tissue used to assess risk of recurrence and inform chemotherapy treatment decisions.