Table 3.

Differences in vitamin D metabolite concentration and odds ratios of 25-hydroxyvitamin D deficiency or insufficiency between deficient and non-deficient Mg status

Parameter	Deficient Mg status	Non-deficient Mg status	Difference or odds ratios with 95%CI	P-value
Primary endpoint
25(OH)D (ng/mL; mean,95%CI)
Unadjusted	17.0 (15.9 to 18.2)	17.3 (16.8 to 17.7)	0.23 (-0.98 to 1.44)	0.71
RS-adjusted	17.1 (16.6 to 17.5)	17.8 (16.6 to 19.1)	0.79 (-0.54 to 2.10)	0.25
RS-matched	5.7 (14.6 to 16.7)	17.1 (16.1 to 18.2)	1.54 (-0.03 to 2.91)	0.06
Secondary Endpoints
Deficient 25(OH)D (%, OR,95%CI)
Unadjusted	32.9	35.6	1.13 (0.87 to 1.45)	0.37
RS-adjusted	-	-	0.83 (0.63 to 1.09)	0.18
RS-matched	39.4	35.3	0.84 (0.60 to 1.17)	0.31
Insufficient 25(OH)D (%, OR,95%CI)
Unadjusted	67.5	66.9	0.97 (0.75 to 1.27)	0.84
RS-adjusted	-	-	0.76 (0.58 to 1.01)	0.06
RS-matched	74.5	67.1	0.69 (0.48 to 0.99)	0.046
24,25(OH)2D (ng/mL; mean,95%CI)
Unadjusted	2.73 (2.81 to 3.05)	2.93 (2.42 to 3.05)	0.20 (-0.14 to 0.54)	0.25
RS-adjusted	2.92 (2.57 to 3.27)	2.88 (2.76 to 3.00)	-0.04 (-0.41 to 0.33)	0.84
RS-matched	2.75 (2.47 to 3.03)	2.55 (2.27 to 2.83)	-0.20 (-0.59 to 0.20)	0.33
Vitamin D metabolite ratio (%, mean,95%CI)
Unadjusted	5.96 (5.64 to 6.79)	6.25 (6.13 to 6.37)	0.29 (-0.09 to 0.63)	0.09
RS-adjusted	6.26 (5.94 to 6.58)	6.21 (6.09 to 6.33)	-0.06 (-0.40 to 0.29)	0.76
RS-matched	5.97 (5.67 to 6.27)	5.97 (5.67 to 6.27)	0.00 (–0.43 to 0.43)	> 0.99
Calcitriol (pg/mL; mean,95%CI)
Unadjusted	34.7 (33.1 to 36.3)	34.7 (34.1 to 35.3)	-0.05 (-1.72 to 1.62)	0.95
RS-adjusted	35.1 (33.3 to 36.4)	34.6 (34.0 to 35.2)	-0.46 (-2.32 to 1.40)	0.63
RS-matched	34.8 (33.3 to 36.4)	33.6 (32.0 to 35.1)	-1.27 (-3.42 to 0.87)	0.24

Abbreviations: 25(OH)D, 25-hydroxyvitamin D; CI, confidence interval; RS, risk score; OR, odds ratio; 24,25(OH)₂D, 24,25-dihydroxyvitamin D