Table 4.
Linear growth model results measuring associations between slope and intercept of three frontal alpha EEG coherence pairs and subsequent AUD symptoms in the trauma-exposed subsample of adolescent male and female COGA participants
| Left frontal-central (LFC) EEG coherence FZ-CZ--F3-C3 |
Right frontal-central (RFC) EEG coherence FZ-CZ--F4-C4 |
Prefrontal interhemispheric (PFI) EEG coherence F8-F4--F7-F3 |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Males | Females | Males | Females | Males | Females | |||||||
| Beta (s.e.) | p | Beta (s.e.) | p | Beta (s.e.) | p | Beta (s.e.) | p | Beta (s.e.) | p | Beta (s.e.) | p | |
| Associations with AUD and PTSD symptoms | ||||||||||||
| Intercept on AUD symptoms | 0.08 (0.45) | 0.862 | 0.53 (0.12) | <0.001 | 4.10 (0.19) | <0.001 | −0.58 (0.66) | 0.377 | 0.41 (0.60) | 0.494 | 0.53 (1.10) | 0.633 |
| Slope on AUD symptoms | −0.91 (0.77) | 0.237 | −0.79 (0.77) | 0.305 | −1.55 (1.26) | 0.218 | −3.16 (1.03) | 0.002 | −1.39 (0.83) | 0.094 | −0.22 (0.58) | 0.700 |
| Intercept on PTSD symptoms | 0.28 (0.15) | 0.066 | 2.65 (0.12) | <0.001 | 2.47 (0.09) | <0.001 | 0.15 (0.18) | 0.419 | 1.05 (0.13) | <0.001 | 1.69 (0.08) | <0.001 |
| Slope on PTSD symptoms | 0.01 (0.48) | 0.992 | −0.48 (0.94) | 0.612 | −0.22 (0.56) | 0.699 | −5.19 (1.52) | 0.001 | −2.02 (0.89) | 0.023 | −0.82 (0.55) | 0.137 |
| Correlation between AUD and PTSD symptoms | 0.01 (0.01) | 0.312 | 0.01 (0.01) | 0.552 | 0.00 (0.01) | 0.863 | 0.01 (0.01) | 0.494 | −0.00 (0.01) | 0.887 | 0.00 (0.01) | 0.718 |
| Observations | 408 | – | 459 | – | 408 | – | 459 | – | 408 | – | 459 | – |
| AIC | 3034.34 | – | 3950.75 | – | 3061.07 | – | 3934.99 | – | 2900.58 | – | 3497.02 | – |
| BIC | 3198.81 | – | 4120.04 | – | 3225.54 | – | 4104.28 | – | 3065.04 | – | 3666.31 | – |
| H0 log-likelihood | −1476.17 | – | −1934.37 | – | −1489.537 | – | −1926.49 | −1409.29 | – | −1707.51 | – | |
| H1 maximum log-likelihood | −1037.24 | – | −1495.84 | – | −1057.53 | – | −1489.05 | −970.62 | – | −1261.84 | – | |
Note: Analyses were limited to individuals who reported at least one traumatic experience during any assessment from baseline to the third follow-up. PTSD symptoms and AUD symptoms represent the lifetime maximum symptoms as reported at the third follow-up assessment. Models account for childhood trauma variables and parental education associations with intercept and slope of EEG coherence. Bold text indicates p-value less than 0.05. Bold italic text indicates p-value less than 0.01.