Table 2.
Acute gastrointestinal injury and clinical variables
|
Variables
|
Non-AGI (n = 30)
|
AGI (n = 45)
|
t/Z
|
P value
|
| Mean bowel sound rate (counts per minute) | 4.343 ± 2.756 | 1.185 ± 1.441 | -5.352 | < 0.001b |
| Duration of bowel sounds (seconds) | 1.579 ± 1.049 | 0.534 ± 0.919 | -5.041 | < 0.001b |
| Amplitude (dB) | 0.121 ± 0.097 | 0.037 ± 0.076 | -5.029 | < 0.001b |
| Average frequency (Hz) | 708.559± 219.649 | 355.458± 238.318 | -5.094 | < 0.001b |
| Interval time (seconds) | 3.977 ± 1.410 | 2.098 ± 1.508 | -4.448 | <0.001b |
| Citrulline (μmol/L) | 19.29 ± 1.46 | 18.47 ± 1.68 | 2.165 | 0.034a |
| Intestinal fatty acid-binding protein (ng/L) | 467 ± 59 | 493 ± 60 | -1.863 | 0.067 |
| Gastrin (ng/L) | 79.45 ± 12.16 | 74.95 ± 12.87 | 1.493 | 0.140 |
| Motilin (ng/L) | 215.20 ± 37.58 | 211.73 ± 38.27 | 0.382 | 0.703 |
| Sequential Organ Failure Assessment score, points | 6 ± 3 | 9 ± 5 | -2.596 | 0.009b |
| Acute Physiology and Chronic Health Evaluation II score, points | 17 ± 6 | 22 ± 9 | -2.430 | 0.018a |
| Hemoglobin (g/L) | 98 ± 26 | 96 ± 21 | 0.418 | 0.678 |
| Platelets (109/L) | 161 ± 104 | 122 ± 89 | -1.553 | 0.120 |
| white blood cell (109/L) | 8.45 ± 3.36 | 10.08 ± 4.41 | -1.462 | 0.144 |
| Neutrophil count (109/L) | 7.32 ± 3.09 | 8.82 ± 436 | -1.697 | 0.094 |
| Percentage of central granulocyte count | 84.9 ± 7.9 | 88.6 ± 6.7 | -1.430 | 0.153 |
| C-reactive protein (mg/L) | 99.3 ± 72.7 | 104.4 ± 80.2 | -0.159 | 0.874 |
| procalcitonin (ng/mL) | 3.768 ± 7.037 | 7.250 ± 12.337 | -1.187 | 0.235 |
| Interleukin 6 (ng/mL) | 103.688 ± 256.797 | 166.78 ± 322.69 | -2.262 | 0.024a |
| Total protein (g/L) | 52.0 ± 6.7 | 49.8 ± 6.3 | 1.421 | 0.160 |
| Albumin (g/L) | 28.6 ± 3.6 | 27.7 ± 4.2 | 0.905 | 0.369 |
| Creatinine (µmol/L) | 115 ± 108 | 109 ± 82 | -0.108 | 0.914 |
| Blood urea nitrogen (mmol/L) | 11.25 ± 6.00 | 11.96 ± 8.16 | -0.132 | 0.895 |
| Serum sodium (mmol/L) | 140.28 ± 5.17 | 138.94 ± 4.90 | -1.070 | 0.284 |
| Serum potassium (mmol/L) | 4.09 ± 0.52 | 4.03 ± 0.42 | 0.509 | 0.613 |
| Serum calcium (mmol/L) | 2.07 ± 0.17 | 2.02 ± 0.15 | 1.397 | 0.167 |
| Serum phosphorus (mmol/L) | 0.94 ± 0.32 | 0.96 ± 0.43 | -0.053 | 0.958 |
| Arterial blood gas potential of hydrogen | 7.457 ± 0.060 | 7.422 ± 0.074 | 2.158 | 0.034a |
| Partial pressure of oxygen (mmHg) | 106.4 ± 37.8 | 105.5 ± 34.9 | -0.024 | 0.981 |
| Partial pressure of carbon dioxide (mmHg) | 36.8 ± 8.9 | 38.0 ± 8.1 | -0.591 | 0.556 |
| Bicarbonate (mmol/L) | 26.4 ± 5.6 | 24.6 ± 4.3 | 1.564 | 0.122 |
| Lactic acid (mmol/L) | 1.2 ± 0.8 | 1.5 ± 1.0 | -1.308 | 0.191 |
| Serum magnesium (mmol/L) | 0.95 ± 0.13 | 0.94 ± 0.13 | 0.186 | 0.853 |
| Body mass index (kg/m2) | 22.52 ± 4.25 | 23.19 ± 5.01 | -0.552 | 0.583 |
| Age (years) | 59 ± 16 | 62 ± 19 | -1.098 | 0.272 |
| Duration of mechanical ventilation (days) | 7 ± 16 | 8 ± 11 | -1.054 | 0.292 |
| Intensive care unit length of stay (days) | 16 ± 16 | 13 ± 12 | -0.774 | 0.439 |
| Hospital length of stay (days) | 19 ± 17 | 20 ± 16 | -0.292 | 0.770 |
a
P < 0.05.
b
P < 0.01.
Data are expressed as mean ± SD. t/Z value is the test statistic, P value is the comparison between the non-acute gastrointestinal injury (AGI) and AGI groups. AGI: Acute gastrointestinal injury.