Table 5.
Acute gastrointestinal injury severity and clinical variables
|
Variables
|
AGI I (n = 32)
|
AGI II (n = 10)
|
AGI III-IV (n = 3)
|
PF/χ²
|
| Mean bowel sound rate (counts per minute) | 1.308 ± 1.610 | 0.942 ± 0.994 | 0.717 ± 0.690 | 0.828 |
| Duration of bowel sounds (seconds) | 0.513 ± 0.795 | 0.719 ± 1.385 | 0.178 ± 0.180 | 0.719 |
| Amplitude (dB) | 0.032 ± 0.043 | 0.065 ± 0.144 | 0.011 ± 0.009 | 0.818 |
| Average frequency (Hz) | 366.215 ± 238.280 | 344.720 ± 256.841 | 287.276 ± 260.841 | 0.858 |
| Interval time (seconds) | 2.180 ± 1.554 | 1.851 ± 1.285 | 2.045 ± 2.171 | 0.854 |
| Citrulline (μmol/L) | 18.47 ± 1.68 | 18.53 ± 1.94 | 18.22 ± 0.88 | 0.973 |
| Intestinal fatty acid-binding protein (ng/L) | 489 ± 58 | 516 ± 61 | 467 ± 68 | 0.364 |
| Gastrin (ng/L) | 72.49 ± 12.11 | 77.07 ± 11.22 | 93.33 ± 13.01 | 0.019a |
| Motilin (ng/L) | 212.23 ± 38.97 | 218.42 ± 33.79 | 186.32 ± 46.98 | 0.459 |
| Sequential Organ Failure Assessment score, points | 9 ± 4 | 9 ± 6 | 12 ± 3 | 0.510 |
| Acute Physiology and Chronic Health Evaluation II score, points | 21 ± 8 | 27 ± 12 | 20 ± 5 | 0.240 |
| Hemoglobin (g/L) | 95 ± 21 | 96 ± 23 | 110 ± 8 | 0.509 |
| Platelets (109/L) | 138 ± 95 | 78 ± 52 | 67 ± 38 | 0.076 |
| White blood cell (109/L) | 10.58 ± 4.78 | 9.07 ± 2.41 | 7.01 ± 2.34 | 0.170 |
| Neutrophil count (109/L) | 9.56 ± 4.61 | 6.84 ± 3.03 | 6.16 ± 1.68 | 0.159 |
| Percentage of central granulocyte count | 89.5 ± 6.0 | 84.9 ± 8.3 | 89.3 ± 7.0 | 0.322 |
| C-reactive protein (mg/L) | 98.2 ± 77.6 | 107.3 ± 96.1 | 159.3 ± 50.3 | 0.410 |
| Procalcitonin (ng/mL) | 7.504 ± 14.053 | 4.888 ± 4.323 | 10.927 ± 7.004 | 0.897 |
| Interleukin 6 (ng/mL) | 164.07 ± 358.46 | 169.29 ± 232.63 | 187.21 ± 170.99 | 0.292 |
| Total protein (g/L) | 50.8 ± 6.3 | 47.1 ± 6.0 | 46.1 ± 4.808 | 0.171 |
| Albumin (g/L) | 28.0 ± 4.4 | 27.2 ± 3.8 | 25.7 ± 3.0 | 0.630 |
| Creatinine (µmol/L) | 111 ± 88 | 94 ± 66 | 131 ± 79 | 0.664 |
| Blood urea nitrogen (mmol/L) | 11.03 ± 6.90 | 10.64 ± 7.24 | 25.19 ± 13.52 | 0.141 |
| Serum sodium (mmol/L) | 138.51 ± 3.96 | 139.12 ± 7.87 | 142.91 ± 3.64 | 0.338 |
| Serum potassium (mmol/L) | 4.02 ± 0.44 | 4.08 ± 0.37 | 4.03 ± 0.46 | 0.791 |
| Serum calcium (mmol/L) | 2.04 ± 0.15 | 2.00 ± 0.16 | 1.92 ± 0.09 | 0.396 |
| Serum phosphorus (mmol/L) | 0.93 ± 0.40 | 1.02 ± 0.58 | 1.10 ± 0.12 | 0.472 |
| Arterial blood gas potential of hydrogen | 7.427 ± 0.075 | 7.397 ± 0.075 | 7.441 ± 0.074 | 0.520 |
| Partial pressure of oxygen (mmHg) | 106.5 ± 39.7 | 103.3 ± 15.7 | 101.7 ± 31.7 | 0.886 |
| Partial pressure of carbon dioxide (mmHg) | 39.0 ± 8.3 | 35.8 ± 7.4 | 34.6 ± 8.7 | 0.435 |
| Bicarbonate (mmol/L) | 25.6 ± 4.3 | 21.8 ± 3.4 | 23.1 ± 2.3 | 0.050 |
| Lactic acid (mmol/L) | 1.4 ± 1.0 | 1.6 ± 1.1 | 1.7 ± 1.3 | 0.722 |
| Serum magnesium (mmol/L) | 0.96 ± 0.14 | 0.91 ± 0.11 | 0.84 ± 0.19 | 0.345 |
| Body mass index (kg/m2) | 23.47 ± 4.96 | 22.07 ± 4.98 | 23.44 ± 7.21 | 0.813 |
| Duration of mechanical ventilation, days | 10 ± 12 | 3 ± 5 | 8 ± 11 | 0.132 |
| Intensive care unit length of stay (days) | 14 ± 13 | 10 ± 10 | 17 ± 11 | 0.552 |
| Hospital length of stay (days) | 21+16 | 11 ± 11 | 32 ± 22 | 0.040a |
| Age (years) | 62 ± 18 | 58 ± 23 | 73 ± 13 | 0.460 |
a
P < 0.05, P value was obtained from the comparison of differences between groups.
Data are expressed as mean ± SD. F/χ² is the test statistic. AGI: Acute gastrointestinal injury.