Table 6.

Role of baicalein in mediating tumor angiogenesis.

Type of cancer	Type of Study	Model	Dosage of baicalein	Pathway involved	Reference
General	In vitro and in vivo	B16F10 cells, Lewis lung carcinoma (LLC) cells, and HUVECs; and pathogen-free C57BL/6 mice	0, 1, 10, 100 and 200 μM; and 1.5 mg/kg	–	[105]
Non-Small Cell Lung Cancer	In vivo	Balb/c male thymic nude mice (6-week-old)	40 mg/kg	Src/Id1 signalling	[106]
Lung cancer	In vitro and in vivo	A549 and HUVECs cell lines; transgenic zebrafish model	0, 1, 4, 5, 8, 10, 25, 50 and 100 μM; and 1–2.5 μM	–	[107]
Gastric cancer	In vitro and in vivo	Cell lines HGC-27, SGC-7901, MGC-803 and BGC-823. 4–6-week-old BALB/c nude female mice	0, 5, 15, 25 and 50 μmol/l; and 50 mg/kg	miR-7/FAK/AKT signalling	[108]