Table 1.
Results table summarising studies included in the review.
| Study | Population (n) | Mean age (years) | Study details | WB/NWB/PWB | Intervention | Results | Complications | DOI |
|---|---|---|---|---|---|---|---|---|
| David G. Armstrong (1997) 17 | 55 (27 male, 28 female). | 58.6 (range 50.1–67.1) | Retrospective (1991–1994) | WB | TCC followed by removable cast walkers and prescription therapeutic shoe | Mean casting time 18.5 ± 10.6 weeks | 4 patients (7.3%) developed ulceration during the follow up period | 10.7547/87507315-87-6-272 |
| David R. Sinacore et al. (1998) 18 | 30 (24 male, 6 Female). | 55 (range N/A) | Retrospective (1991–1996) | PWB | PWB in TCC using a heel touch-down method for balance. Casts changed at 1- or 2-week intervals. | Mean casting time 86 days ± 45 days (range: 22–224 days). | 4 patients (13%) went on to have further exacerbations of Charcot neuroarthropathy in the same foot. These required a further 6 week in TCC. | 10.1016/s1056-8727(98) 00006-3 |
| Michael S. Pinzur (2006) 19 | 9 (4 men and 5 women) | 58.2 (range 39–72) | Prospective | WB | TCC with cast changed every 2 weeks, followed by commercial depth-inlay shoes and custom accommodative orthotics. | Mean casting time time of 9.2 weeks (range 8–16). | 1 patient (11%) developed ulceration during follow up | 10.1177/107110070602700503 |
| Leo J. de Souza et al. (2008) 20 | 27 (6 male, 21 female) 7 patients with bilateral involvement resulting in 34 affected feet | N/A | Prospective (1988–2006) | WB | TCC with casts changed at weekly intervals | Mean casting time 14 weeks (range: 4–20). 33 out of the 34 feet reached disease resolution. | 10 patients (37%) developed ulceration during follow up | 10.2106/JBJS.F.01523 |
| Danielle A. Griffiths (2021) 10 | 27 (18 male, 9 female) | 57.9 (range N/A) | Retrospective (2012–2015) | WB | TCC followed by transition into Charcot Restraint Orthotic Walker, knee-high removable offloading boot (e.g. CAM walker or therapeutic footwear. | Median casting time 4.3 months (IQR, 2.7–7.8) | 21 patients (78%) of patients reported minor cast issues including skin irritation and asymmetry pain. 6 patients (22.2%) went on to have soft tissue or bony reconstructive surgery. | 10.1186/s13047-021-00477-5 |
CAM: controlled ankle motion.