Table 1.

Course of treatment in a 2-year-old female, spayed Akita Inu infected with Leishmania infantum

Day	Treatment	Diagnosis	L. infantum status
−5 months	Cyclosporine 10 mg/kg once daily orally Prednisolone 0.8 mg/kg once daily orally	Primary immune-mediated hemolytic anemia	—
Day 0 (first presentation)	Allopurinol 9.3 mg/kg twice daily orally Meglumine antimonate 92 mg/kg once daily subcutaneouslya Prednisolone 0.6 mg/kg once daily orally Stopped cyclosporine	Leishmaniasis	Serology 1:640 (positive)b
Day 38	Allopurinol 9.3 mg/kg twice daily orally Meglumine antimonate 92 mg/kg once daily subcutaneously Prednisolone 0.4 mg/kg once daily orally		—
Day 73	Allopurinol 7.4 mg/kg twice daily orally Prednisolone 0.2 mg/kg once daily orally Meglumine antimonate finished		—
Day 143	Allopurinol 7.4 mg/kg twice daily orally Prednisolone stopped		Serology 1:640 (positive)b
Day 679	Allopurinol 7.4 mg/kg twice daily orally Meglumine antimonate 80 mg/kg once daily subcutaneously		Serology 1:640 (positive)b PCR positiveb
Day 722	Allopurinol 7.4 mg/kg twice daily orally Meglumine antimonate finished		—

^aGlucantime 1.5 g/5 ml, Sanofi-Aventis France, Gentilly Cedex

^bOrbio laboratory, Bron, France