Table 2.
Body weight, complete blood count, biochemical parameters, and parasitological status in a 2-year-old female, spayed Akita Inu infected with Leishmania infantum from first presentation (day 0, D0) to day 1316 (D1316) recorded in the Clinique Veterinaire Alliance (Bordeaux, France)
| Parameter | RI | D0 | D38 | D73 | D143 | D244 | D351 | D416 | D625 | D679 | D736 | D875 | D1050 | D1270 | D1316 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BW (kg) | — | 27.0 | 27.4 | — | 26.0 | 24.3 | 25.2 | 24.4 | — | 22.9 | 23.6 | 25.5 | 26.0 | 25.3 | 26.2 |
| Change in BW (%) | — | 100.0 | 101.5 | — | 96.3 | 90.0 | 93.3 | 90.4 | — | 84.8 | 87.4 | 94.4 | 96.3 | 93.7 | 97.0 |
| Complete blood counta | |||||||||||||||
| RBC (× 1012/l) | 5.65–8.87 | 5.08 | 6.93 | 7.35 | 7.14 | 8.12 | 8.31 | — | 7.22 | — | 7.29 | 7.53 | 8.3 | — | 8.29 |
| HGB (g/l) | 131–205 | 97 | 128 | 143 | 138 | 160 | 156 | — | 125 | — | 113 | 141 | 154 | — | 125 |
| HCT (l/l) | 0.37–0.62 | 0.27 | 0.37 | 0.39 | 0.39 | 0.46 | 0.46 | — | 0.37 | 0.35 | 0.42 | 0.47 | — | 0.38 | |
| WBC (× 1012/l) | 5.1–16.8 | 12.9 | 9.7 | 7.0 | 6.7 | 6.4 | 7.1 | — | 8.9 | — | 16.9 | 6.1 | 4.14 | — | 6.1 |
| Seg (× 109/l) | 3.0–11.6 | 10.2 | 7.8 | 4.0 | 4.3 | 3.2 | 3.8 | — | 5.8 | — | 12.9 | 2.9 | 1.9 | — | 3.4 |
| Lymphs (× 109/l) | 1.1–5.1 | 1.8 | 1.5 | 2.4 | 2.0 | 2.7 | 2.9 | — | 2.6 | — | 2.8 | 2.5 | 1.9 | — | 2.4 |
| Eos (× 109/l) | 0.06–1.23 | 0.01 | 0.01 | 0.20 | 0.15 | 0.24 | 0.19 | — | 0.14 | — | 0.25 | 0.41 | 0.19 | — | 0.09 |
| Monos (× 109/l) | 0.2–1.1 | 0.8 | 0.4 | 0.3 | 0.3 | 0.2 | 0.2 | — | 0.3 | — | 0.9 | 0.2 | 0.1 | — | 0.2 |
| CHr (pg) | 22.3–29.6 | 17.0 | 17.8 | 18.6 | 18.0 | 17.7 | 21.4 | — | 17.4 | — | 20.6 | 21.9 | 21.9 | — | 17.0 |
| THR (× 109/l) | 148–484 | 121 | 201 | 166 | 241 | 144 | 125 | — | 119 | — | 165 | 142 | 107 | — | 74 |
| Ret (× 109 /l) | 10.0–110.0 | 63.5 | 83.9 | 17.6 | 75.7 | 78.0 | 46.5 | — | 69.3 | — | 44.5 | 29.2 | 67.2 | — | 38.1 |
| Biochemistryb | |||||||||||||||
| TP (g/l) | 52–82 | 87 | 83 | 72 | — | 72 | 70 | — | 81 | 88 | 82 | 69 | 73 | 84 | 87 |
| Alb (g/l) | 23–40 | 25 | 40 | 36 | — | 33 | 32 | — | 30 | 28 | 29 | 32 | 34 | 28 | 29 |
| Glob (g/l) | 25–45 | 52 | 43 | 36 | — | 39 | 38 | — | 51 | 60 | 53 | 37 | 39 | 56 | 58 |
| A/G | — | 0.7 | 0.9 | 1.0 | — | 0.8 | 0.8 | — | 0.6 | 0.5 | 0.5 | 0.9 | 0.9 | 0.5 | 0.5 |
| Urea (g/l) | 0.15–0.57 | 0.32 | — | — | — | — | — | — | 0.18 | — | — | — | — | 0.09 | — |
| Crea (mg/l) | 5.0–18.0 | 8.7 | 6.0 | 10.2 | 12.0 | 15.0 | 18.1 | 15.2 | 14.4 | 23.3 | 19.4 | 16.7 | 16.5 | 15.0 | 18.7 |
| Bil (mg/l) | < 9.0 | 3.5 | — | — | — | — | — | — | 1.6 | — | — | — | — | 1.0 | — |
Bold indicates values outside reference intervals
A/G albumin-to-globulin ratio, Alb albumin, Bil bilirubin, BW body weight, CHr reticulocyte hemoglobin content, Crea creatinine, Eos eosinophilic granulocytes, Glob globulin, HCT hematocrit, HGB hemoglobin, Lymphs lymphocytes, Monos monocytes, RBCs red blood cells, Seg segmented neutrophilic granulocytes, Ret reticulocytes, THR platelets, TP total protein, WBCs white blood cells
aIDEXX ProCyte One Hematology Analyzer
bIDEXX Catalyst One Chemistry Analyzer