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. 2024 Dec 16;17:506. doi: 10.1186/s13071-024-06583-0

Table 3.

Complete blood count, biochemical parameters, and parasitological status in a 2-year-old female, spayed Akita Inu infected with Leishmania infantum in the LABOKLIN laboratory (Bad Kissingen, Germany) on day 1322 after first presentation

Parameter Reference interval Values
Complete blood counta
 Red blood cells (× 1012/l) 5.5–8.5 8.76
 Hemoglobin (g/l) 150–190 132
 Hematocrit (l/l) 0.44–0.52 0.47
 White blood cells (× 1012/l) 6.0–12.0 7.1
 Segmented (× 109/l) 3.0–9.0 3.4
 Bands (× 109/l)  < 0.6 0.0
 Lymphocytes (× 109/l) 1.0–3.6 3.4
 Eosinophils (× 109/l) 0.04–0.6 0.1
 Monocytes (× 109/l) 0.04–0.5 0.3
 Hypochromasia Negative Negative
 Anisocytosis Negative Negative
 Platelets (× 109/l) 150–500 93
Biochemistryb
 Alpha-amylase (U/l)  < 1,650.0 1,618
 DGGR-lipase (U/l)  < 120.0 31.8
 Glucose (mmol/l) 3.05–6.1 5.2
 Fructosamine (µmol/l)  < 374 253
 Triglycerides (mmol/l)  < 3.9 0.95
 Cholesterol (mmol/l) 3.1–10.1 7.2
 Bilirubin (µmol/l)  < 3.4  < 0.1
 Alkaline phosphatase (U/l)  < 147 64
 Glutamate dehydrogenase (U/l)  < 8.0 2.0
 Gamma-glutamyl transferase (U/l)  < 10.0 1.7
 Alanine transaminase (U/l)  < 88.0 23.7
 Aspartate aminotransferase (U/l)  < 51.0 27.5
 Creatine kinase (U/l)  < 200.0 47.0
 Total protein (g/l) 54.0–75.0 75.9
 Albumin (g/l) 25.0–44.0 29.4
 Globulin (g/l)  < 45.0 46.5
 Urea (mmol/l) 3.3–8.3 4.7
 Creatinine (µmol/l)  < 125 122
 Phosphorus (mmol/l) 0.7–1.6 0.8
 Magnesium (mmol/l) 0.6–1.3 0.9
 Calcium (mmol/l) 2.3–3.0 2.4
 Sodium (mmol/l) 140–155 141
 Potassium (mmol/l) 3.5–5.1 4.3
 Iron (µmol/l) 15–45 10.4
 C-reactive protein (mg/l)  < 15.0 38.2
Leishmania testing
 Leishmania IFATc  ≤ 1:64 1:1024
 Leishmania ELISAd  < 11 LE 22.1
 Leishmania qPCR (/ml EDTA blood) 10 (positive)

Segmented segmented neutrophilic granulocytes, Bands banded neutrophilic granulocytes, EDTA ethylenediamine tetraacetic acid, ELISA enzyme-linked immunosorbent assay, IFAT immunofluorescence antibody test, qPCR quantitative polymerase chain reaction,

aSysmex XN-V analyzer, Sysmex Deutschland, Norderstedt, Germany

bCobas 8000, Roche Deutschland Holding GmbH, Mannheim, Germany

cMegaFLUO® LEISH, MegaCor Diagnostik GmbH, Hörbranz, Austria

dNovaTec VetLine Leishmania ELISA, Immundiagnostica GmbH, Dietzenbach, Germany

Bold values are outside the reference intervals of the commercial LABOKLIN laboratory (Bad Kissingen, Germany)