Table 4. Predictor Markers of Persistent Joint Pain in Chikungunya Infection.
Study | Follow-up (months) | Outcome | Sample size (n) | Time of markers evaluation |
Contrast of markers' concentrations (Recovered patients as
reference group) |
|||
Chronic | Recovered | Higher | Lower | Non difference | ||||
| ||||||||
Hoarau, 2010 [10] | 12 | Joint pain > 1 joint, > 3 months | 9 | 6 | 5 days | CRP | TNF-α, IL-8, IL-6, IFN-γ, IFN-α, IL-12, IL-4, IL-13 | |
Chang, 2018 [39] | 20 | Joint pain | 121 | 121 | Acute phase | IL-1β, IL-6, TNF-α, IL-10, IL-12, IL-13, IL-17, IL-2, IL-4, IL-5 |