TABLE 1.
VFL | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Case No. | Sex | Age (yrs)* | Ep Dur (yrs) | BL | Postop | Cognitive Outcome† | Path | Sz Freq/Mo | Sz Type | EC‡ | AEDs |
1 | M | 26 | 21 | 24 | 32 | Good | Atrophy | 1 | CPS, SPS, CPS/G | A | Levetiracetam, lamotrigine |
2 | M | 28 | 12 | 19 | 12 | Poor | Enlarge (horn) | 2 | CPS, CPS/G | A | Levetiracetam, oxcarbazepine |
3 | F | 41 | 36 | 11 | 3 | Poor | MTS | 16 | CPS, SPS | C | Levetiracetam, valproic acid, phenobarbital |
4 | M | 30 | 11 | 21 | 20 | Good | MTS | 2 | CPS, GTC | A | Levetiracetam |
5 | F | 50 | 31 | 21 | 13 | Poor | Atrophy | 7 | CPS, CPS/G | C | Phenytoin |
6 | M | 47 | 42 | 21 | 11 | Poor | Hippo atrophy | 15 | CPS | A | Carbamazepine, irbesartan |
7 | F | 42 | 4 | 18 | 8 | Poor | MTS | 1 | CPS | A | Lamotrigine, methimazole |
8 | F | 32 | 8 | 17 | 18 | Good | MTS | 1 | CPS, CPS/G | C | Lamotrigine, carbamazepine |
9 | F | 53 | 40 | 13 | 18 | Good | MTS | 5 | CPS, GTC | A | Lamotrigine, carbamazepine |
10 | M | 65 | 45 | 16 | 20 | Good | Hippo atrophy | 7 | CPS | A | Topiramate, olanzapine |
11 | F | 39 | 26 | 16 | 21 | Good | Hippo atrophy | 1 | CPS | A | Valproic acid, phenobarbital, carbamazepine |
12 | M | 60 | 56 | 18 | 11 | Poor | MTS | 2 | CPS, SPS | A | Levetiracetam |
13 | F | 52 | 32 | 23 | 17 | Poor | Enlarge (horn) | 1 | CPS, GTC | A | Lamotrigine, carbamazepine |
14 | F | 41 | 37 | 26 | 25 | Good | MTS | 2 | CPS, GTC | A | Venlafaxine, lamotrigine, levetiracetam |
15 | F | 26 | 5 | 14 | 17 | Good | Atrophy | 20 | CPS | A | Diazepam, levetiracetam, topiramate |
Mean (SD) | 42 (12) | 27 (16) | 18 (4) | 16 (7) | 5 (6) |
AEDs = antiepileptic drugs; BL = baseline; CPS = complex partial seizures; CPS/G = complex partial seizures with secondary generalization; EC = postsurgical Engel Class I subscore; enlarge = enlargement; Ep Dur = epilepsy duration; GTC = generalized tonic-clonic seizures; Hippo = hippocampal; MTS = mesial temporal sclerosis; Path = temporal lobe pathology; SPS = simple partial seizures; Sz = seizure; VFL = verbal (semantic) fluency.
Age at baseline scan.
Based on RCI.