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Pam3CSK4 attenuates AngII-induced gene expression of CCR5 and CXCR3 in aneurismal lesions measured by real-time PCR (a) and Western blot (b) (n = 4/group). TAK-779, a CCR5 antagonist, decreases the incidence and severity of AAA formation measured by incidence (c) and aortic diameter (d). *p < 0.05 versus control, #p < 0.05 versus AngII alone, **p < 0.01 versus control, ##p < 0.01 versus AngII alone.
