Table 2.
Logistic regression analysis for factors associated with cancer cachexia (N = 411).
| Characteristics | Multivariate |
|
|---|---|---|
| OR (95% CI) | P-value | |
| Age | ||
| ≥75 years (vs. <75 years) | 1.21 (0.66–2.21) | .531 |
| Sex | ||
| female (vs. male) | 0.52 (0.24–1.14) | .102 |
| Smoking status | ||
| current or former smoker (vs. never) | 0.55 (0.22–1.35) | .192 |
| ECOG PS | ||
| 2–4 (vs. 0–1) | 2.29 (0.87–2.79) | .138 |
| Histology | ||
| squamous (vs. non-squamous) | 1.22 (0.74–2.00) | .429 |
| Driver mutation | ||
| positive (vs. negative or not investigated) | 3.19 (1.06–9.60) | .040 |
| ECOG PS | ||
| 2–4 (vs. 0–1) | 2.29 (1.13–4.64) | .021 |
| PD-L1 status | ||
| 50–89% (vs.≧90%) | 0.98 (0.55–1.74) | .933 |
| Stage | ||
| IVA or IVB (vs. Recurrence) | 1.60 (0.72–3.55) | .247 |
| BMI | ||
| <20 (vs.≧20) | 7.59 (4.36–13.2) | <.001 |
| Liver metastasis | ||
| yes (vs. no) | 1.26 (0.60–2.63) | .548 |
| Brain metastasis | ||
| yes (vs. no) | 0.93 (0.43–2.02) | .858 |
ECOG PS, Eastern Cooperative Oncology Group Performance Status; PD-L1, programmed death ligand 1; BMI, body mass index; OR, odds ratio; CI, confidence interval.