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. 1999 Jul;67(7):3317–3328. doi: 10.1128/iai.67.7.3317-3328.1999

TABLE 5.

Immunization with hemolysin decreases recovery of H. ducreyi 35000 but not 35000ΔAPC in the temperature-dependent rabbit model

Expt Recovery of H. ducreyia
35000
35000ΔAPC
Control rabbits Immunized rabbits P Control rabbits Immunized rabbits P
Aspirates
 Expt 1 4/6b 0/6b 0/6b 0/6b
 Expt 2 3/4c 0/3b 0/3b 2/3b
 Expt 3 2/4c 0/4c 2/4c 1/4c
  Total 9/14 0/13 0.0026 2/13 3/13 0.4795
Biopsies
 Expt 2 4/4c 2/3b 2/4c 2/3b
 Expt 3 5/6b 1/6b 5/6c 5/6b
  Total 9/10 3/9 0.0429 7/10 7/9 0.7518
   Totald 18/24 3/22 0.0004 9/23 10/22 0.6942
a

Number of lesions with viable organisms/number of lesions sampled. 

b

Lesions sampled were from 105-, 106-, and 107-CFU inocula. 

c

Lesions sampled were from 104-, 105-, 106-, and 107-CFU inocula. 

d

Aspirates and biopsies combined.