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. Author manuscript; available in PMC: 2024 Dec 17.
Published in final edited form as: Surg Obes Relat Dis. 2023 Jan 2;19(8):799–807. doi: 10.1016/j.soard.2022.12.038

Table 5.

Complications of VTE prophylaxis during hospitalization

Questions Medical Directors Membership Total P- value

Do you modify the VTE prophylaxis protocol when concerned about bleeding risk?
 No 36 (31.9%) 44 (35.5%) 80 (33.8%) .556
 Yes 77 (68.1%) 80 (64.5%) 157 (66.2%)
In your practice, have you seen any patients who received extended chemoprophylaxis and developed PE?
 No 92 (82.1%) 99 (79.2%) 191 (80.6%) .557
 Yes 20 (17.9%) 26 (20.8%) 46 (19.4%)
Which postoperative complications would keep you from using extended chemoprophylaxis?*
 Infection 2 (1%) 0 (0%) 2 (.5%) .222
 Return to operating room 8 (4.2%) 5 (2.6%) 13 (3.4%) .228
 Any bleeding 23 (12%) 26 (13.5%) 49 (12.8%) .955
 Bleeding requiring chemoprophylaxis cessation and observation 53 (27.6%) 48 (25%) 101 (26.3%) .141
 Bleeding requiring chemoprophylaxis cessation and blood transfusion 48 (25%) 48 (25%) 96 (25%) .464
 Bleeding requiring chemoprophylaxis cessation and reoperation 41 (21.4%) 46 (24%) 87 (22.7%) .968
 Other 1 (.5%) 0 (0%) 1 (.3%) .470
 None 16 (8.3%) 19 (9.9%) 35 (9.1%) .837
In your practice, did your patients have any side effects from extended VTE chemoprophylaxis?*
 Hematoma 36 (22.5%) 36 (21.2%) 72 (21.8%) .625
 Infection 1 (.6%) 0 (0%) 1 (.3%) .478
 Bleeding requiring chemoprophylaxis cessation and observation 31 (19.4%) 32 (18.8%) 63 (19.1%) .794
 Bleeding requiring chemoprophylaxis cessation and blood transfusion 22 (13.8%) 22 (13%) 44 (13.3%) .746
 Bleeding requiring chemoprophylaxis cessation and reoperation 12 (7.5%) 11 (6.5%) 23 (7%) .658
 Other 5 (3.1%) 2 (1.2%) 7 (2.1%) .263
 None 53 (33.1%) 67 (39.4%) 120 (36.4%) .246

VTE = venous thromboembolism; PE = pulmonary embolism.

Data are expressed as n (%).

P value is calculated using Chi-square or Fisher’s exact test when appropriate.

*

Multiple response questions.